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http://hdl.handle.net/2445/44244
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DC Field | Value | Language |
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dc.contributor.author | Barragán, Flavia | - |
dc.contributor.author | Moreno Martínez, Virtudes | - |
dc.contributor.author | Marchán Sancho, Vicente | - |
dc.date.accessioned | 2013-06-14T07:50:44Z | - |
dc.date.available | 2013-06-14T07:50:44Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1359-7345 | - |
dc.identifier.uri | http://hdl.handle.net/2445/44244 | - |
dc.description.abstract | The first dichloroplatinum(II) conjugates of dicarba analogues of octreotide , which is expected to act as a"tumour-targeting device", have been efficiently synthesized following a stepwise solid-phase approach; these compounds emulate the mechanism of cisplatin since they form a 1,2-intrastrand cross-link with two consecutive guanines of an oligonucleotide. | - |
dc.format.extent | 3 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Royal Society of Chemistry | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.1039/B909698A | - |
dc.relation.ispartof | Chemical Communications, 2009, p. 4705-4707 | - |
dc.relation.uri | http://dx.doi.org/10.1039/B909698A | - |
dc.rights | (c) Barragán, Flavia et al., 2009 | - |
dc.source | Articles publicats en revistes (Química Inorgànica i Orgànica) | - |
dc.subject.classification | ADN | - |
dc.subject.classification | Química bioinorgànica | - |
dc.subject.classification | Quimioteràpia del càncer | - |
dc.subject.classification | Cèl·lules canceroses | - |
dc.subject.classification | Toxicitat dels medicaments | - |
dc.subject.other | DNA | - |
dc.subject.other | Bioinorganic chemistry | - |
dc.subject.other | Cancer chemotherapy | - |
dc.subject.other | Cancer cells | - |
dc.subject.other | Drug toxicity | - |
dc.title | Solid-phase synthesis and DNA binding studies of dichloroplatinum(II) conjugates of dicarba analogues of octreotide as a new anticancer drugs | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 568522 | - |
dc.date.updated | 2013-06-14T07:50:44Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
Files in This Item:
File | Description | Size | Format | |
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568522.pdf | 251.71 kB | Adobe PDF | View/Open |
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