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http://hdl.handle.net/2445/48630| Title: | Preparation of alpha-labeled aldehydes by base-catalyzed exchange reactions |
| Author: | Ariza Piquer, Xavier Asins Muñoz, Guillermina García Gómez, Jordi García Hegardt, Fausto Makowski, Kamil Serra i Cucurull, Dolors Velasco Turbau, Javier |
| Keywords: | Trastorns del metabolisme dels lípids Bioquímica Aldehids Disseny de medicaments Medicina nuclear Lipid metabolism disorders Biochemistry Aldehydes Drug design Nuclear medicine |
| Issue Date: | 2010 |
| Publisher: | John Wiley & Sons |
| Abstract: | A simple, efficient protocol for the preparation of α-labeled aldehydes based on H/D exchange catalyzed by 4-(N,N-dimethylamino)pyridine or Et3N is described. High chemical yields and ratios of isotope incorporation were obtained even when small amounts (1 mmol) of aldehyde were used. |
| Note: | Versió preprint del document publicat a: http://dx.doi.org/10.1002/jlcr.1759 |
| It is part of: | Journal of Labelled Compounds and Radiopharmaceuticals, 2010, vol. 53, num. 8, p. 556-558 |
| URI: | http://hdl.handle.net/2445/48630 |
| Related resource: | http://dx.doi.org/10.1002/jlcr.1759 |
| ISSN: | 0362-4803 |
| Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) Articles publicats en revistes (Bioquímica i Biomedicina Molecular) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 578380.pdf | 163.23 kB | Adobe PDF | View/Open |
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