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http://hdl.handle.net/2445/50383Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Sánchez-Moya, Albert | - |
| dc.contributor.author | Pedroso Muller, Enrique | - |
| dc.contributor.author | Grandas Sagarra, Anna | - |
| dc.date.accessioned | 2014-02-18T15:19:49Z | - |
| dc.date.available | 2014-12-31T23:02:05Z | - |
| dc.date.issued | 2013 | - |
| dc.identifier.issn | 1359-7345 | - |
| dc.identifier.uri | http://hdl.handle.net/2445/50383 | - |
| dc.description.abstract | A novel method to synthesize cyclic oligonucleotides (5- to 26-mer) using the thiol-maleimide reaction is described. The target molecules were obtained after subsequent removal of thiol and maleimide protecting groups from 5′-maleimido-3′-thiol-derivatized linear precursors. Retro-Diels-Alder conditions deprotecting the maleimide simultaneously promoted cyclization cleanly and in high yield. | - |
| dc.format.extent | 3 p. | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | eng | - |
| dc.publisher | Royal Society of Chemistry | - |
| dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/ 10.1039/C2CC35357A | - |
| dc.relation.ispartof | Chemical Communications, 2013, vol. 49, p. 309-311 | - |
| dc.relation.uri | http://dx.doi.org/10.1039/C2CC35357A | - |
| dc.rights | (c) Sánchez, Albert et al., 2013 | - |
| dc.source | Articles publicats en revistes (Química Inorgànica i Orgànica) | - |
| dc.subject.classification | Bioquímica | - |
| dc.subject.classification | Àcids nucleics | - |
| dc.subject.classification | Bacteris | - |
| dc.subject.classification | Microbiologia | - |
| dc.subject.classification | Ciclització (Química) | - |
| dc.subject.other | Biochemistry | - |
| dc.subject.other | Nucleic acids | - |
| dc.subject.other | Bacteria | - |
| dc.subject.other | Microbiology | - |
| dc.subject.other | Ring formation (Chemistry) | - |
| dc.title | Oligonucleotide cyclization: The thiol-maleimide reaction revisited | eng |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/acceptedVersion | - |
| dc.identifier.idgrec | 619951 | - |
| dc.date.updated | 2014-02-18T11:02:41Z | - |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
| dc.identifier.pmid | 23183555 | - |
| Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 619951.pdf | 321.21 kB | Adobe PDF | View/Open |
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