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http://hdl.handle.net/2445/51423| Title: | Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers |
| Author: | Pérez de Vega, M.J. García-López, M.T. Zaccaro, Laura Royo Expósito, Miriam Albericio Palomera, Fernando Fernández-Carvajal, A. Ferrer-Montiel, A. González-Muñiz, R. |
| Keywords: | Síntesi en fase sólida Canals iònics Bioquímica Analgèsics Ciències de la salut Proteïnes Dianes farmacològiques Solid-phase synthesis Ion channels Biochemistry Analgesics Medical sciences Proteins Drug targeting |
| Issue Date: | 15-Jul-2010 |
| Publisher: | MDPI Publishing |
| Abstract: | Trp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N-terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists. |
| Note: | Reproducció del document publicat a: http://dx.doi.org/10.3390/molecules15074924 |
| It is part of: | Molecules, 2010, vol. 15, num. 7, p. 4924-4933 |
| URI: | http://hdl.handle.net/2445/51423 |
| Related resource: | http://dx.doi.org/10.3390/molecules15074924 |
| ISSN: | 1420-3049 |
| Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
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| 613899.pdf | 247.84 kB | Adobe PDF | View/Open |
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