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http://hdl.handle.net/2445/51423
Title: | Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers |
Author: | Pérez de Vega, M.J. García-López, M.T. Zaccaro, Laura Royo Expósito, Miriam Albericio Palomera, Fernando Fernández-Carvajal, A. Ferrer-Montiel, A. González-Muñiz, R. |
Keywords: | Síntesi en fase sólida Canals iònics Bioquímica Analgèsics Ciències de la salut Proteïnes Dianes farmacològiques Solid-phase synthesis Ion channels Biochemistry Analgesics Medical sciences Proteins Drug targeting |
Issue Date: | 15-Jul-2010 |
Publisher: | MDPI Publishing |
Abstract: | Trp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N-terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.3390/molecules15074924 |
It is part of: | Molecules, 2010, vol. 15, num. 7, p. 4924-4933 |
URI: | http://hdl.handle.net/2445/51423 |
Related resource: | http://dx.doi.org/10.3390/molecules15074924 |
ISSN: | 1420-3049 |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
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