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http://hdl.handle.net/2445/54980| Title: | First enantioselective synthesis of isagarin, a natural product isolated from Pentas longiflora Oliv. |
| Author: | Jacobs, Jan Claessens, Sven Mol, Eva de El Hady, Samir Minguillón Llombart, Cristina Álvarez Domingo, Mercedes Kimpe, Norbert de |
| Keywords: | Síntesi asimètrica Productes naturals Asymmetric synthesis Natural products |
| Issue Date: | 30-Apr-2010 |
| Publisher: | Elsevier B.V. |
| Abstract: | For the first time, an enantioselective synthesis of both 1R,4S-isagarin 1a and 1S,4R-isagarin 1b was achieved starting from 1,4-dimethoxy-2-vinylnaphtalene 2. The key steps involve a Sharpless asymmetric dihydroxylation and reaction with an acetonylating pyridinium ylid. |
| Note: | Versió postprint del document publicat a: http://dx.doi.org/10.1016/j.tet.2010.04.105 |
| It is part of: | Tetrahedron, 2010, vol. 66, num. 27-28, p. 5158-5160 |
| URI: | http://hdl.handle.net/2445/54980 |
| Related resource: | http://dx.doi.org/10.1016/j.tet.2010.04.105 |
| ISSN: | 0040-4020 |
| Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 585961.pdf | 53.96 kB | Adobe PDF | View/Open |
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