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http://hdl.handle.net/2445/64765Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Navarro Brugal, Gemma | - |
| dc.contributor.author | Borroto Escuela, Dasiel Oscar | - |
| dc.contributor.author | Fuxe, Kjell | - |
| dc.contributor.author | Franco Fernández, Rafael | - |
| dc.date.accessioned | 2015-04-08T13:23:30Z | - |
| dc.date.available | 2015-04-08T13:23:30Z | - |
| dc.date.issued | 2014-09-30 | - |
| dc.identifier.issn | 1664-042X | - |
| dc.identifier.uri | http://hdl.handle.net/2445/64765 | - |
| dc.description.abstract | Caveolae are membrane micro-domains enriched in cholesterol, sphingolipids and caveolins, which are transmembrane proteins with a hairpin-like structure. Caveolae participate in receptor-mediated trafficking of cell surface receptors and receptor-mediated signaling. Furthermore, caveolae participate in clathrin-independent endocytosis of membrane receptors. On the one hand, caveolins are involved in vascular and cardiac dysfunction. Also, neurological abnormalities in caveolin-1 knockout mice and a link between caveolin-1 gene haplotypes and neurodegenerative diseases have been reported. The aim of this article is to present the rationale for considering caveolae as potential targets in cardiovascular and neurological diseases. | - |
| dc.format.extent | 8 p. | - |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | eng | - |
| dc.publisher | Frontiers Media | - |
| dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.3389/fphys.2014.00370 | - |
| dc.relation.ispartof | Frontiers in Physiology , 2014, vol. 5, p. 1-8 | - |
| dc.relation.uri | http://dx.doi.org/10.3389/fphys.2014.00370 | - |
| dc.rights | cc-by (c) Navarro et al., 2014 | - |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
| dc.source | Articles publicats en revistes (Bioquímica i Biomedicina Molecular) | - |
| dc.subject.classification | Malalties del sistema nerviós | - |
| dc.subject.classification | Membranes cel·lulars | - |
| dc.subject.classification | Malalties cardiovasculars | - |
| dc.subject.classification | Proteïnes de membrana | - |
| dc.subject.other | Nervous system Diseases | - |
| dc.subject.other | Cell membranes | - |
| dc.subject.other | Cardiovascular diseases | - |
| dc.subject.other | Membrane proteins | - |
| dc.title | Potential of caveolae in the therapy of cardiovascular and neurological diseases. | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.identifier.idgrec | 649524 | - |
| dc.date.updated | 2015-04-08T13:23:31Z | - |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
| dc.identifier.pmid | 25324780 | - |
| Appears in Collections: | Articles publicats en revistes (Bioquímica i Biomedicina Molecular) | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 649524.pdf | 902.84 kB | Adobe PDF | View/Open |
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