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Title: Colorectal cancer screening: strategies to select populations with moderate risk for disease
Author: Navarro, Matilde
Binefa i Rodríguez, Gemma
Peris, Mercè
Blanco Guillermo, Ignacio
Guardiola, Jordi
Espinàs Piñol, Josep Alfons
Borràs Andrés, Josep Maria
Catalan Colorectal Cancer Screening Pilot Program Group
Keywords: Càncer colorectal
Medicina preventiva
Assistència mèdica
Factors de risc en les malalties
Colorectal cancer
Preventive medicine
Medical care
Risk factors in diseases
Issue Date: 10-Jul-2009
Publisher: Aran Ediciones
Abstract: Objective: to analyse the association between rectal bleeding or a family history of colorectal cancer (CRC) and the results obtained in two rounds of a CRC screening pilot programme performed in L'Hospitalet, Barcelona, Spain. Subjects: males and females (50-69 years) were the target population. Together with the invitation letter, they received a questionnaire in which they were asked about rectal bleeding, family history of CRC and related neoplasms. The screening test was a guaiac-based faecal occult blood test (FOBT), and colonoscopy for positive tests. Results: 25,829 FOBT were performed in 18,405 individuals. Information on rectal bleeding and a family history of CRC were obtained for 9,849 and 9,865 cases, respectively. Male sex (OR = 1.32), 60-69 years of age (OR = 1.48), rectal bleeding (OR = 1.84) and history of CRC (OR = 1.54) were independent predictors of positive FOBT. With regard to colonoscopy, a greater risk of diagnosing advanced neoplasm was observed among men (OR = 2.47) and subjects with a family history of CRC (OR = 1.98). Conclusions: CRC screening programmes must have instruments that make it possible to select the candidate population and the possibility of offering a study suited to the risk of individuals who are not susceptible to population screening by means of FOBT.
Note: Reproducció del document publicat a:
It is part of: Revista Española de Enfermedades Digestivas, 2009, vol. 101, num. 2, p. 855-860
ISSN: 1130-0108
Appears in Collections:Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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