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http://hdl.handle.net/2445/69166
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DC Field | Value | Language |
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dc.contributor.author | Requena-Méndez, Ana | - |
dc.contributor.author | Aldasoro, Edelweiss | - |
dc.contributor.author | Muñoz, José | - |
dc.contributor.author | Moore, David A. J. | - |
dc.date.accessioned | 2016-02-03T09:04:30Z | - |
dc.date.available | 2016-02-03T09:04:30Z | - |
dc.date.issued | 2015-05-21 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://hdl.handle.net/2445/69166 | - |
dc.description.abstract | RATIONALE: Objective, reproducible quantification of the extent of abnormalities seen on a chest radiograph would improve the user-friendliness of a previously proposed severity scoring system for pulmonary tuberculosis and could be helpful in monitoring response to therapy, including in clinical trials. METHODS: In this study we report the development and evaluation of a simple tool using free image editing software (GIMP) to accurately and reproducibly quantify the area of affected lung on the chest radiograph of tuberculosis patients. As part of a pharmacokinetic study in Lima, Peru, a chest radiograph was performed on patients with pulmonary tuberculosis and this was subsequently photographed using a digital camera. The GIMP software was used by two independent and trained readers to estimate the extent of affected lung (expressed as a percentage of total lung area) in each radiograph and the resulting radiographic SCORE. RESULTS: 56 chest radiographs were included in the reading analysis. The Intraclass correlation coefficient (ICC) between the 2 observers was 0.977 (p<0.001) for the area of lung affected and was 0.955 (p<0.001) for the final score; and the kappa coefficient of Interobserver agreement for both the area of lung affected and the score were 0.9 (p<0.001) and 0.86 (p<0.001) respectively. CONCLUSIONS: This high level of between-observer agreement suggests that this freely available software could constitute a simple and useful tool for robust evaluation of individual and serial chest radiographs. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Public Library of Science (PLoS) | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0128044 | - |
dc.relation.ispartof | PLoS One, 2015, vol. 10, num. 5, p. e0128044 | - |
dc.relation.uri | http://dx.doi.org/10.1371/journal.pone.0128044 | - |
dc.rights | cc by (c) Requena-Mendez et al., 2015 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | - |
dc.source | Articles publicats en revistes (ISGlobal) | - |
dc.subject.classification | Tuberculosi | - |
dc.subject.classification | Radiografia | - |
dc.subject.classification | Programari lliure | - |
dc.subject.classification | Processament d'imatges | - |
dc.subject.classification | Perú | - |
dc.subject.other | Tuberculosis | - |
dc.subject.other | Radiography | - |
dc.subject.other | Open source software | - |
dc.subject.other | Image processing | - |
dc.subject.other | Peru | - |
dc.title | Robust and Reproducible Quantification of the Extent of Chest Radiographic Abnormalities (And It's Free!) | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 685937 | - |
dc.date.updated | 2016-02-02T15:33:28Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 25996917 | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
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685937.pdf | 3.79 MB | Adobe PDF | View/Open |
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