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Title: | Proteins of Bartonella bacilliformis: Candidates for Vaccine Development |
Author: | Henriquez-Camacho, Cesar Ventosilla, Palmira Minnick, Michael F. Ruiz, Joaquim Maguina, Ciro |
Keywords: | Malalties infeccioses Vacunes Bacteriologia mèdica Amèrica del Sud Communicable diseases Vaccines Medical bacteriology South America |
Issue Date: | 6-Aug-2015 |
Publisher: | Hindawi Publishing Corporation |
Abstract: | Bartonella bacilliformis is the etiologic agent of Carrion's disease or Oroya fever. B. bacilliformis infection represents an interesting model of human host specificity. The notable differences in clinical presentations of Carrion's disease suggest complex adaptations by the bacterium to the human host, with the overall objectives of persistence, maintenance of a reservoir state for vectorial transmission, and immune evasion. These events include a multitude of biochemical and genetic mechanisms involving both bacterial and host proteins. This review focuses on proteins involved in interactions between B. bacilliformis and the human host. Some of them (e.g., flagellin, Brps, IalB, FtsZ, Hbp/Pap31, and other outer membrane proteins) are potential protein antigen candidates for a synthetic vaccine. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.1155/2015/702784 |
It is part of: | International Journal of Peptides, 2015, vol. 2015, num. , p. 1-6 |
URI: | http://hdl.handle.net/2445/69244 |
Related resource: | http://dx.doi.org/10.1155/2015/702784 |
ISSN: | 1687-9767 |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
Files in This Item:
File | Description | Size | Format | |
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henriquez-camacho2015_1999.pdf | 2.01 MB | Adobe PDF | View/Open |
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