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Title: Directional and fluctuating asymmetry in finger and a-b ridge counts in psychosis: a case-control study
Author: Saha, Sukanta
Loesch, Danuta
Chant, David
Welham, Joy
El-Saadi, Ossama
Fañanás Saura, Lourdes
Mowry, Bryan
McGrath, John J.
Keywords: Psicosi
Fluctuating Asymmetry measures
Finger and a-b ridge counts
Issue Date: 2003
Publisher: BioMed Central
Abstract: Background: Several studies have reported alterations in finger and a-b ridge counts, and their derived measures of asymmetry, in schizophrenia compared to controls. Because ridges are fully formed by the end of the second trimester, they may provide clues to disturbed early development. The aim of this study was to assess these measures in a sample of patients with psychosis and normal controls.Methods: Individuals with psychosis (n = 240), and normal controls (n = 228) were drawn from a catchment-area case-control study. Differences in finger and a-b ridge count and Fluctuating Asymmetry were assessed in three group comparisons (non-affective psychosis versus controls; affective psychosis versus controls; non-affective psychosis versus affective psychosis). The analyses were performed separately for males and females. Results: There were no significant group differences for finger nor a-b ridge counts. While there were no group difference for Directional Asymmetry, for Fluctuating Asymmetry measures men with non-affective psychosis had significantly higher fluctuating asymmetry of the index finger ridge count (a) when compared to controls (FA-correlation score, p = 0.02), and (b) when compared to affective psychosis (adjusted FA-difference score, p = 0.04). Conclusion: Overall, measures of finger and a-b ridge counts, and their derived measures of directional and fluctuating asymmetry were not prominent features of psychosis in this sample. While directional asymmetry in cerebral morphology is reduced in schizophrenia, this is not reflected in dermatoglyphic variables.
Note: Reproducció del document publicat a
It is part of: BMC Psychiatry, 2003, vol. 3, núm. 3
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ISSN: 1471-244X
Appears in Collections:Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)

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