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Title: Cerebral infarction in diabetes: Clinical pattern, stroke subtypes,and predictors of in-hospital mortality
Author: Arboix, A. (Adrià)
Rivas, Antoni
García-Eroles, Luis
Marcos, Lourdes de
Massons, Joan
Oliveres, Montserrat
Keywords: Diabetis
Complicacions (Medicina)
Infart cerebral
Hospital mortality
Diabetes complications
Cerebral Infarctio
Issue Date: 2005
Publisher: BioMed Central
Abstract: Background: To compare the characteristics and prognostic features of ischemic stroke in patients with diabetes and without diabetes, and to determine the independent predictors of in-hospital mortality in people with diabetes and ischemic stroke. Methods: Diabetes was diagnosed in 393 (21.3%) of 1,840 consecutive patients with cerebral infarction included in a prospective stroke registry over a 12-year period. Demographic characteristics, cardiovascular risk factors, clinical events, stroke subtypes, neuroimaging data, and outcome in ischemic stroke patients with and without diabetes were compared. Predictors of in-hospital mortality in diabetic patients with ischemic stroke were assessed by multivariate analysis. Results: People with diabetes compared to people without diabetes presented more frequently atherothrombotic stroke (41.2% vs 27%) and lacunar infarction (35.1% vs 23.9%) (P < 0.01). The in-hospital mortality in ischemic stroke patients with diabetes was 12.5% and 14.6% in those without (P = NS). Ischemic heart disease, hyperlipidemia, subacute onset, 85 years old or more, atherothrombotic and lacunar infarcts, and thalamic topography were independently associated with ischemic stroke in patients with diabetes, whereas predictors of in-hospital mortality included the patient's age, decreased consciousness, chronic nephropathy, congestive heart failure and atrial fibrillation. Conclusion: Ischemic stroke in people with diabetes showed a different clinical pattern from those without diabetes, with atherothrombotic stroke and lacunar infarcts being more frequent. Clinical factors indicative of the severity of ischemic stroke available at onset have a predominant influence upon in-hospital mortality and may help clinicians to assess prognosis more accurately.
Note: Reproducció del document publicat a
It is part of: BMC Neurology, 2005, vol. 5, núm. 9
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ISSN: 1471-2377
Appears in Collections:Articles publicats en revistes (Medicina)

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