Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/97242
Title: | Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation |
Author: | Balcells, Eva Gimeno Santos, Elena Batlle, Jordi de Ramon, Maria Antonia Rodríguez, Esther Benet, Marta Farrero, Eva Ferrer Monreal, Antonio Guerra, Stefano Ferrer, Jaume Sauleda, Jaume Barberà i Mir, Joan Albert Agustí García-Navarro, Àlvar Rodríguez-Roisin, Robert Gea Guiral, Joaquim Antó i Boqué, Josep Maria García Aymerich, Judith PAC-COPD Study Group |
Keywords: | Malalties pulmonars obstructives cròniques Assistència hospitalària Estudi de casos Epidemiologia Chronic obstructive pulmonary diseases Hospital care Case studies Epidemiology |
Issue Date: | 17-Jan-2015 |
Publisher: | BioMed Central |
Abstract: | Background Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD. Methods The PAC-COPD cohort included 342 COPD patients hospitalised for the first time for an exacerbation of COPD (2004-2006). Patients were extensively characterised using sociodemographic, clinical and functional variables, and the cohort was followed-up through 2008. We defined "undiagnosed COPD" by the absence of any self-reported respiratory disease and regular use of any pharmacological respiratory treatment. Results Undiagnosed COPD was present in 34% of patients. They were younger (mean age 66 vs. 68 years, p = 0.03), reported fewer symptoms (mMRC dyspnoea score, 2.1 vs. 2.6, p < 0.01), and had a better health status (SGRQ total score, 29 vs. 40, p < 0.01), milder airflow limitation (FEV1% ref., 59% vs. 49%, p < 0.01), and fewer comorbidities (two or more, 40% vs. 56%, p < 0.01) when compared with patients with an established COPD diagnosis. Three months after hospital discharge, 16% of the undiagnosed COPD patients had stopped smoking (vs. 5%, p = 0.019). During follow-up, annual hospitalisation rates were lower in undiagnosed COPD patients (0.14 vs. 0.25, p < 0.01); however, this difference disappeared after adjustment for severity. Mortality was similar in both groups. Conclusions Undiagnosed COPD patients have less severe disease and lower risk of re-hospitalisation when compared with hospitalised patients with known COPD. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.1186/1471-2466-15-4 |
It is part of: | BMC Pulmonary Medicine, 2015, vol. 15, p. 4 |
URI: | http://hdl.handle.net/2445/97242 |
Related resource: | http://dx.doi.org/10.1186/1471-2466-15-4 |
ISSN: | 1471-2466 |
Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
658546.pdf | 635.29 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License