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http://hdl.handle.net/2445/99052
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DC Field | Value | Language |
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dc.contributor.author | Guignard, Guillaume Michel Pablo | - |
dc.contributor.author | Llor Brunés, Núria | - |
dc.contributor.author | Molins i Grau, Elies | - |
dc.contributor.author | Bosch Cartes, Joan | - |
dc.contributor.author | Amat Tusón, Mercedes | - |
dc.date.accessioned | 2016-05-30T17:30:36Z | - |
dc.date.available | 2017-04-15T22:01:21Z | - |
dc.date.issued | 2016-04-15 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.uri | http://hdl.handle.net/2445/99052 | - |
dc.description.abstract | A convergent synthesis of fluvirucinin B1 from acid ent-6a and nitrile ent-9, involving an organocopper coupling, a stereoselective allylation, a ring-closing metathesis reaction, and a stereoselective hydrogenation as the key steps, is reported. The starting building blocks have been prepared in a straightforward manner from a common phenylglycinol-derived lactam 1. An unprecedented regioselective oxidation of phenylglycinol-derived secondary amines 5 to carboxylic acids 6 has been developed. | - |
dc.format.extent | 4 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | American Chemical Society | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.1021/acs.orglett.6b00513 | - |
dc.relation.ispartof | Organic Letters, 2016, vol. 18, num. 81, p. 1788-1791 | - |
dc.relation.uri | http://dx.doi.org/10.1021/acs.orglett.6b00513 | - |
dc.rights | (c) American Chemical Society , 2016 | - |
dc.source | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) | - |
dc.subject.classification | Síntesi orgànica | - |
dc.subject.classification | Lactames | - |
dc.subject.other | Organic synthesis | - |
dc.subject.other | Lactams | - |
dc.title | Enantioselective total synthesis of fluvirucinin B1 | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 659330 | - |
dc.date.updated | 2016-05-30T17:30:41Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 27046224 | - |
Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) Articles publicats en revistes (Institut de Biomedicina (IBUB)) |
Files in This Item:
File | Description | Size | Format | |
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659330.pdf | 572.23 kB | Adobe PDF | View/Open |
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