# name
Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas

# metadata.dc.contributor.author[].value
Estrach Panella, Ma. Teresa (María Teresa)

# metadata.dc.description.abstract[].value
p15(INK4b), p16(INK4a) and O(6)-methylguanine DNA methyltransferase (MGMT) gene hypermethylation was studied in 22 patients with primary cutaneous T-cell lymphomas (CTCL). p15(INK4b) and p16(INK4a) inactivation is present in early and advanced disease and seems to be independent of disease stage. MGMT inactivation may play a pathogenetic role in a subset of CTCL.

# metadata.dc.source[].value
Articles publicats en revistes (Ciències Clíniques)

# metadata.dc.title[].value
Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas