# name
CTDquerier: A Bioconductor R package for Comparative
                Toxicogenomics DatabaseTM data extraction, visualization and
                enrichment of environmental and toxicological studies

# metadata.dc.description.abstract[].value
Biomedical studies currently include a large volume of
                genomic and environmental factors for studying the etiology of
                human diseases. R/Bioconductor projects provide several tools
                for performing enrichment analysis at gene-pathway level,
                allowing researchers to develop novel hypotheses. However, there
                is a need to perform similar analyses at the chemicals-genes or
                chemicals-diseases levels, to provide complementary knowledge of
                the causal path between chemicals and diseases. While the
                Comparative Toxicogenomics DatabaseTM (CTD) provides information
                about these relationships, there is no software for integrating
                it into R/Bioconductor analysis pipelines. CTDquerier helps
                users to easily download CTD data and integrate it in the
                R/Bioconductor framework. The package also contains functions
                for visualizing CTD data and performing enrichment analyses. We
                illustrate how to use the package with a real data analysis of
                asthma-related genes. CTDquerier is a flexible and easy-to-use
                Bioconductor package that provides novel hypothesis about the
                relationships between chemicals and diseases. Availability and
                implementation: CTDquerier R package is available through
                Bioconductor and its development version at
                https://github.com/isglobal-brge/CTDquerier. Contact:
                juanr.gonzalez@isglobal.org. Supplementary information:
                Supplementary data are available at Bioinformatics online.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.1093/bioinformatics/bty326

# metadata.dc.rights[].value
cc by-nc (c) Hernández Ferrer, Carles; González, Juan R., 2018

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
CTDquerier: A Bioconductor R package for Comparative
                Toxicogenomics DatabaseTM data extraction, visualization and
                enrichment of environmental and toxicological studies