# name
Neumonías adquiridas en la comunidad en pacientes con enfermedad pulmonar obstructiva crónica tratados con corticoides inhalados u otros broncodilatadores. Estudio PNEUMOCORT

# metadata.dc.description.abstract[].value
OBJECTIVES: To analyse the risk of pneumonia and/or
                exacerbations in patients with chronic obstructive pulmonary
                disease (COPD) who receive treatment with inhaled
                corticosteroids (CI), in comparison with those who are not
                treated with inhaled corticosteroids (NCI). To estimate the risk
                of pneumonia according to CI dose. DESIGN: Population-based
                cohort study. SETTING: Primary Healthcare. Institut Catala de la
                Salut. PARTICIPANTS: Patients >/=45 years-old diagnosed with
                COPD between 2007 and 2009 in the Information System for
                Research in Primary Care (SIDIAP). INTERVENTION: Two cohorts;
                patients initiating CI and patients initiating bronchodilators
                after COPD diagnosis. MAIN MEASUREMENTS: Demographics, smoking,
                medical history, pneumonias, exacerbations, vaccinations, and
                drug therapy. RESULTS: A total of 3,837 patients were included,
                58% in the CI and 42% in the NCI group. Higher incidence rates
                of pneumonia and exacerbations were detected in the CI group
                compared with the NCI (2.18 vs. 1.37). The risk of pneumonia and
                severe exacerbations was not significantly different between
                groups, HR; 1.17 (95% CI; 0.87-1.56) and 1.06 (95% CI;
                0.87-1.31), respectively. Patients in the CI group had a higher
                risk of mild exacerbations, HR; 1.28 (95% CI; 1.10-1.50).
                Variables associated with a higher risk of pneumonia were age,
                diabetes, previous pneumonias and bronchitis, very severe COPD,
                treatment with low doses of beta2-adrenergic or anticholinergic
                agents, and previous treatment with oral corticosteroids.
                CONCLUSIONS: There were no differences between cohorts in the
                risk of pneumonia and severe exacerbations. The risk of mild
                exacerbations was higher in the CI group. Pneumonias and severe
                exacerbations were more frequent in patients with severe COPD
                and in patients receiving high doses of CI.

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Neumonías adquiridas en la comunidad en pacientes con enfermedad pulmonar obstructiva crónica tratados con corticoides inhalados u otros broncodilatadores. Estudio PNEUMOCORT