# name
Hypoxaemia in Mozambican children < 5 years of age admitted
                to hospital with clinical severe pneumonia: clinical features
                and performance of predictor models

# metadata.dc.description.abstract[].value
OBJECTIVE: To determine the prevalence of hypoxaemia among
                under-five children admitted to hospital with clinical severe
                pneumonia, and to assess the performance to diagnose hypoxaemia
                of models based on clinical signs. METHODS: We conducted a
                hospital-based survey in a district hospital from Southern
                Mozambique. RESULTS: A total of 825 children were recruited
                after obtaining an informed consent. The prevalence of
                hypoxaemia on admission was 27.9%, and 19.8% of these children
                died (OR compared to non-hypoxaemic children 3.22, 95%CI 1.98 -
                5.21, p<0.001). The model with larger area under the ROC
                curve (AUC-ROC) to predict hypoxaemia included cyanosis or
                thoracoabdominal breathing or respiratory rate >/= 70 breaths
                per minute. None of the models performed well when tested in
                different case scenarios of oxygen availability through
                mathematical modelling, with over 50% of hypoxaemic children not
                receiving oxygen even in favourable case scenarios. CONCLUSIONS:
                Clinical signs alone or in combination are not suitable to
                diagnose hypoxaemia. The use of pulse oximeters should be
                strongly encouraged. This article is protected by copyright. All
                rights reserved.

# metadata.dc.relation.isformatof[].value
Versió postprint del document publicat a:
                http://dx.doi.org/10.1111/tmi.12738

# metadata.dc.relation.ispartof[].value
Tropical Medicine & International Health, 2016

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Hypoxaemia in Mozambican children < 5 years of age admitted
                to hospital with clinical severe pneumonia: clinical features
                and performance of predictor models