# name
Synthesis and characterization of new HIV-1 antiviral agents

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Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2024, Tutor: Vicente Marchán Sancho

# metadata.dc.description.abstract[].value
HIV is a virus that, unfortunately, has spread throughout planet Earth. This virus causes a disease called AIDS, acquired immunodeficiency syndrome. Currently, there is no cure for this virus, but there are treatments that allow HIV-positive people to live with it. For this reason, new treatments are being sought to completely eradicate HIV. In this project, a new antiviral agent against HIV has been synthesized on a large scale and fully characterized by 1H and 13C NMR and mass spectrometry. This new antiviral agent is based on a terphenyl structure containing three benzene rings linked by single bonds and functionalized with aliphatic chains terminated with guanidinium groups. The new antiviral agent was designed to mimic a secondary structure of the Rev protein and, consequently, block the RRE-Rev complex and stop HIV replication

# metadata.dc.title[].value
Synthesis and characterization of new HIV-1 antiviral agents

# metadata.dc.title.alternative[].value
Síntesi i caracterització de nous agents antivirals del VIH-1