# name
Embryonic Neural Stem Cell Differentiation to Aldynoglia Induced by Olfactory Bulb Ensheathing Cell-Conditioned Medium

# metadata.dc.description.abstract[].value
Although the relevance of glial cells in regulating brain activity was predicted by Ramon y
Cajal more than a century ago (García-Marín et al., 2007), it was not until almost fifty years
ago that initial descriptions of a close functional relationship between neuroglia and
neuronal perikarya (Hyden, 1962) or axonal processes (Blunt et al, 1965) began to reveal that
neurons and glial cells operate as functional units in the central nervous system (CNS).
However, this functional interaction has only been more carefully studied and analysed in
the last few decades, generating a substantial increase in research on the roles of neuron–
glia interactions in the control of brain function. Glial cells have subsequently been
implicated in many functions, including: guiding the migration of neurons in early
development, axonal guidance and being responsible for their integrity, forming the
necessary scaffold for neuronal architecture and neural protection and proliferation by
trophic effects, modulating neurodegenerative processes, and also being critical participants
in synaptic transmission, and key regulators of neurotransmitter release...

# metadata.dc.relation.ispartof[].value
Chapter 19 in: Atwood, Craig. 2011. Embryonic Stem Cells: The Hormonal Regulation of Pluripotency and Embryogenesis. ISBN: 978-953-51-6430-2. DOI: 10.5772/589. pp: 365-382.

# metadata.dc.rights[].value
cc by (c) Ortuño Sahagún, Daniel et al., 2011

# metadata.dc.source[].value
Llibres / Capítols de llibre (Farmacologia, Toxicologia i Química Terapèutica)

# metadata.dc.title[].value
Embryonic Neural Stem Cell Differentiation to Aldynoglia Induced by Olfactory Bulb Ensheathing Cell-Conditioned Medium