# name
Homogeneous Crystal Nucleation Near a Metastable Fluid-Fluid Phase Transition

# metadata.dc.contributor.author[].value
Stanley, H. Eugene (Harry Eugene), 1941-

# metadata.dc.description.abstract[].value
Several scenarios exist for the protein crystallization and aggregation in solutions near a metastable fluid-fluid phase separation below the solubility line. Based on computations, it was proposed that the fluid-fluid critical point enhances the crystallization rate by many orders of magnitude, while, based on experiments, it was proposed that the fluid-fluid spinodal controls the crystallization rate. Using molecular dynamic simulations for an isotropic model with sticky interaction, we show that neither of these scenarios adequately describes the crystallization mechanism near a metastable fluid-fluid phase separation. We find that the emergence of the high-density fluid inside the spinodal drastically enhances the crystal nucleation in the subcritical region following Ostwald's rule of stages.

# metadata.dc.source[].value
Articles publicats en revistes (Física de la Matèria Condensada)

# metadata.dc.title[].value
Homogeneous Crystal Nucleation Near a Metastable Fluid-Fluid Phase Transition