# name
Naturally Acquired Humoral Immunity against Malaria Parasites
in Non-Human Primates from the Brazilian Amazon, Cerrado and
Atlantic Forest.

# metadata.dc.description.abstract[].value
Plasmodium - Plasmodium brasilianum - P. malariae -
P. malariae - P. falciparum - P. vivax - Plasmodium content: -
 "Non-human primates (NHPs) have been shown to be infected by
parasites of the genus " - ", the etiological agent of malaria
                in humans, creating potential risks of zoonotic transmission. "
                - ", a parasite species similar to " - " of humans, have been
                described in NHPs from Central and South America, including
                Brazil. The merozoite surface protein 1 (MSP1), besides being a
                malaria vaccine candidate, is highly immunogenic. Due to such
                properties, we tested this protein for the diagnosis of parasite
                infection. We used recombinant proteins of " - " MSP1, as well
                as of " - " and " - ", for the detection of antibodies anti-MSP1
                of these parasite species, in the sera of NHPs collected in
                different regions of Brazil. About 40% of the NHP sera were
                confirmed as reactive to the proteins of one or more parasite
                species. A relatively higher number of reactive sera was found
                in animals from the Atlantic Forest than those from the Amazon
                region, possibly reflecting the former more intense parasite
                circulation among NHPs due to their proximity to humans at a
                higher populational density. The presence of " - " positive NHPs
                in the surveyed areas, being therefore potential parasite
                reservoirs, needs to be considered in any malaria surveillance
                program."

# metadata.dc.rights[].value
cc by (c) Ferreira Monteiro, Eliana et al, 2020

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Naturally Acquired Humoral Immunity against Malaria Parasites
in Non-Human Primates from the Brazilian Amazon, Cerrado and
Atlantic Forest.