# name
Quantifying primaquine effectiveness and improving adherence: a
                round table discussion of the APMEN Vivax Working Group

# metadata.dc.description.abstract[].value
The goal to eliminate malaria from the Asia-Pacific by 2030
                will require the safe and widespread delivery of effective
                radical cure of malaria. In October 2017, the Asia Pacific
                Malaria Elimination Network Vivax Working Group met to discuss
                the impediments to primaquine (PQ) radical cure, how these can
                be overcome and the methodological difficulties in assessing
                clinical effectiveness of radical cure. The salient discussions
                of this meeting which involved 110 representatives from 18
                partner countries and 21 institutional partner organizations are
                reported. Context specific strategies to improve adherence are
                needed to increase understanding and awareness of PQ within
                affected communities; these must include education and health
                promotion programs. Lessons learned from other disease programs
                highlight that a package of approaches has the greatest
                potential to change patient and prescriber habits, however
                optimizing the components of this approach and quantifying their
                effectiveness is challenging. In a trial setting, the reactivity
                of participants results in patients altering their behaviour and
                creates inherent bias. Although bias can be reduced by
                integrating data collection into the routine health care and
                surveillance systems, this comes at a cost of decreasing the
                detection of clinical outcomes. Measuring adherence and the
                factors that relate to it, also requires an in-depth
                understanding of the context and the underlying sociocultural
                logic that supports it. Reaching the elimination goal will
                require innovative approaches to improve radical cure for vivax
                malaria, as well as the methods to evaluate its effectiveness.

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Quantifying primaquine effectiveness and improving adherence: a
                round table discussion of the APMEN Vivax Working Group