# name
Effect of a Probiotic Combination on Clinical and Microbiological Oral Parameters in Head and Neck Cancer Patients: A Randomised Clinical Trial

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Patients with head and neck cancer undergoing radiotherapy frequently experience xerostomia and disturbances in the oral bacterial balance, which can significantly impair their quality of life. This study investigated whether a 30-day daily intake of a probiotic combination could enhance salivary function and reduce disease-associated oral bacteria. Participants were randomly assigned to receive either probiotics or a placebo. By the end of the intervention, those in the probiotic group showed notable improvements in stimulated salivary flow and a reduction in overall bacterial counts, particularly Fusobacterium nucleatum. These results suggest that probiotics may represent a safe and effective approach to prevent or mitigate radiotherapy-induced oral complications. This study highlights the potential role of probiotics as a simple and supportive measure to improve oral health and overall well-being during cancer treatment recovery.

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cc-by (c) Pereira-Riveros, Tanya et al., 2025

# metadata.dc.source[].value
Articles publicats en revistes (Patologia i Terapèutica Experimental)

# metadata.dc.title[].value
Effect of a Probiotic Combination on Clinical and Microbiological Oral Parameters in Head and Neck Cancer Patients: A Randomised Clinical Trial