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Clinical, nutritional and immunological characteristics of
                HIV-infected children in an area of high HIV prevalence

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OBJECTIVES: To evaluate the clinical, nutritional and
                neurodevelopment status of HIV-infected children in a high HIV
                prevalence area. METHODS: All HIV-infected children under 15
                years of age attending an outpatient clinic of Mozambique
                between April and May 2010 were recruited. Clinical data were
                collected and physical examination was performed. RESULTS: In
                all, 140 children were recruited. The median age at HIV
                diagnosis was 2.1 years. Fifty-one percent of the children were
                classified in WHO clinical Stages 3 or 4. Median age of
                antiretroviral treatment commencement was 3.9 years. Overall,
                68% were undernourished, mainly stunted. Forty-four percent
                failed to pass the national psychomotor developmental test.
                CONCLUSIONS: The pathways for early HIV diagnosis and start of
                antiretrovirals in children should be improved in Mozambique.
                Malnutrition, especially stunting, and developmental delay were
                highly prevalent. Further research focused on early diagnosis of
                neurocognitive disorders and on the indications of
                antiretroviral treatment commencement based on chronic
                malnutrition is required.

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Versió postprint del document publicat a:
                http://dx.doi.org/10.1093/tropej/fmv038

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Journal of Tropical Pediatrics, 2015, vol. 61, num. 4, p.
                286-294

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Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Clinical, nutritional and immunological characteristics of
                HIV-infected children in an area of high HIV prevalence