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Role of MITF in IgE and MRGPRX2-dependent mast cell activation

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Universitat de Barcelona. Departament de Biomedicina

# metadata.dc.description.abstract[].value
[eng] Anaphylaxis is a severe allergic reaction triggered by allergens to certain foods,
medicines, insect venom, and other substances. Anaphylactic shock can be fatal if
not treated. Mast cells are the effector cells in anaphylaxis, and mast cell
transcriptional factors are crucial in controlling the production of mediators.
In summary, this thesis shows the relevance of microphthalmia associatedtranscription
factor (MITF) in IgE and MRGPRX2-dependent mast cell activation.
Thus, MITF and MITF-dependent genes may become targets to treat IgE or
MRGPRX2-dependent pathologies.

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Tesis Doctorals - Departament - Biomedicina

# metadata.dc.title[].value
Role of MITF in IgE and MRGPRX2-dependent mast cell activation