# name
Implications of asymptomatic infection for the natural history
                of selected parasitic tropical diseases

# metadata.dc.description.abstract[].value
Progress has been made in the control or elimination of
                tropical diseases, with a significant reduction of incidence.
                However, there is a risk of re-emergence if the factors fueling
                transmission are not dealt with. Although it is essential to
                understand these underlying factors for each disease,
                asymptomatic carriers are a common element that may promote
                resurgence; their impact in terms of proportion in the
                population and role in transmission needs to be determined. In
                this paper, we review the current evidence on whether or not to
                treat asymptomatic carriers given the relevance of their role in
                the transmission of a specific disease, the efficacy and
                toxicity of existing drugs, the Public Health interest, and the
                benefit at an individual level, for example, in Chagas disease,
                to prevent irreversible organ damage. In the absence of other
                control tools such as vaccines, there is a need for safer drugs
                with good risk/benefit profiles in order to change the paradigm
                so that it addresses the complete infectious process beyond
                manifest disease to include treatment of non-symptomatic
                infected persons.

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Implications of asymptomatic infection for the natural history
                of selected parasitic tropical diseases