# name
Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015)

# metadata.dc.description.abstract[].value
Objective: The Plan of Information on Acute Respiratory Infections in Catalonia (PIDIRAC) included the surveillance
of severe hospitalized cases of laboratory-confrmed infuenza (SHCLCI) in 2009. The objective of this study was to
determine the clinical, epidemiological and virological features of SHCLCI recorded in 12 sentinel hospitals during fve
infuenza seasons.
Results: From a sample of SHCLCI recorded during the 5 infuenza epidemics seasons from 2010–2011 to 2014–2015,
Cases were confrmed by PCR and/or viral isolation in cell cultures from respiratory samples. A total of 1400 SHCLCI
were recorded, 33% required ICU admission and 12% died. The median age of cases was 61 years (range 0–101 years);
70.5% were unvaccinated; 80.4% received antiviral treatment (in 79.6 and 24% of cases within 48 h after hospital
admission and the onset of symptoms, respectively); infuenza virus A [37.9% A (H1N1)pdm09, 29.3% A (H3N2)] was
identifed in 87.7% of cases. Surveillance of SHCLCI provides an estimate of the severity of seasonal infuenza epidemics
and the identifcation and characterization of at-risk groups in order to facilitate preventive measures such as vaccination
and early antiviral treatment.

# metadata.dc.rights[].value
cc by (c) Torner Gràcia, Núria et al., 2018

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Articles publicats en revistes (Medicina)

# metadata.dc.title[].value
Descriptive study of severe hospitalized cases of laboratory-confirmed influenza during five epidemic seasons (2010–2015)