# name
Leukoerythroblastosis in a Young Child with Severe Malaria and
                Superimposed Gram Negative Infection

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Background: Leukoerythroblastosis, a non-specific and often
                short-lasting response of the bone marrow to different diseases
                such as malignancies or infections, is characterized by the
                presence in the peripheral blood of immature red and white
                cells. Methods: We present a case of leukoerythoblastosis
                occurring in a 24 months old Mozambican girl, in the context of
                a severe malaria episode and an associated urinary tract
                infection. Peripheral blood smear was used for diagnosis of
                malaria and leukoerythroblastosis. Enterobacter cloacae
                isolation and antibiotic susceptibility testing were performed
                by conventional microbiology. Results: Peripheral blood smear
                was positive for Plasmodium falciparum and showed a
                leukoerythroblastosis with red cell anisopoikilocytosis and left
                shifted neutrophils. Urine culture confirmed the presence of a
                multi-resistant E. cloacae. Treatment of underlying conditions
                resolved the leukoerythroblastic reaction. Conclusions:
                Leukoerythroblastosis may be related to different infectious
                diseases and may also appear in the context of severe malaria.
                Bacterial superinfection needs to be investigated.

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Versió postprint del document publicat a:
                http://dx.doi.org/10.1093/tropej/fmx101

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Leukoerythroblastosis in a Young Child with Severe Malaria and
                Superimposed Gram Negative Infection