# name
Cancer mortality in an international cohort of reinforced
                plastics workers exposed to styrene: a reanalysis

# metadata.dc.description.abstract[].value
OBJECTIVE: To investigate the carcinogenicity of styrene by
                reanalysing data from a previous international cohort study of
                workers in the reinforced plastics industry. METHODS: Mortality
                from cancers of prior interest was analysed with more detailed
                consideration of exposure-response relations and an updated
                classification of leukaemias and lymphomas in data from a
                previous international cohort study of 37 021 reinforced
                plastics workers exposed to airborne styrene. RESULTS: Increased
                mortality from non-Hodgkin's lymphoma (NHL) was associated with
                the mean level of exposure to styrene in air (relative risk (RR)
                2.31, 95% CI 1.29 to 4.12 per 100 ppm), but not with cumulative
                styrene exposure. Similar associations with mean exposure were
                observed for the oesophagus (RR 2.44, 95% CI 1.11 to 5.36 per
                100 ppm) and pancreas (RR 1.89, 95% CI 1.17 to 3.09).
                Oesophageal cancer mortality was also associated with cumulative
                styrene exposure lagged 20 years (RR 1.16, 95% CI 1.03 to 1.31).
                No other cancer, including lung cancer, was associated with any
                indicator of styrene exposure. CONCLUSION: This reanalysis does
                not substantially change the conclusions of the original study
                with respect to NHL or lung cancer but new evidence concerning
                cancers of the oesophagus and pancreas merits further
                investigation.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.1136/oemed-2018-105131

# metadata.dc.relation.ispartof[].value
Occupational and Environmental Medicine, 2018

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Cancer mortality in an international cohort of reinforced
                plastics workers exposed to styrene: a reanalysis