# name
Use of adenoviral vectors with a minimal cytomegalovirus promoter

# metadata.dc.description.abstract[].value
E1-deleted recombinant adenoviruses 5 are widely used as gene vectors for
basic and clinical research. Most adenoviral constructions bear an expression
cassette inserted into the E1 region of their genome close to the 5′ end and include a heterologous promoter. The major immediate early human cytomegalovirus (hCMV) and the Rous sarcoma virus promoters, which have fairly high and consistent activity, are among the most extensively used. Nevertheless, expression of delivered protein from these promoters is often excessive, and weaker transcriptional activity would be desirable.

# metadata.dc.rights[].value
cc-by (c) Ferrer-Martínez, Andreu et al., 2018

# metadata.dc.source[].value
Articles publicats en revistes (Patologia i Terapèutica Experimental)

# metadata.dc.title[].value
Use of adenoviral vectors with a minimal cytomegalovirus promoter