# name
Polyamidoamine nanoparticles as nanocarriers for the drug
                delivery to malaria parasite stages in the mosquito vector

# metadata.dc.description.abstract[].value
Malaria is arguably one of the main medical concerns worldwide
                because of the numbers of people affected, the severity of the
                disease and the complexity of the life cycle of its causative
                agent, the protist Plasmodium spp. With the advent of
                nanoscience, renewed hopes have appeared of finally obtaining
                the long sought-after magic bullet against malaria in the form
                of a nanovector for the targeted delivery of antimalarial
                compounds exclusively to Plasmodium-infected cells, thus
                increasing drug efficacy and minimizing the induction of
                resistance to newly developed therapeutic agents.
                Polyamidoamine-derived nanovectors combine into a single
                chemical structure drug encapsulating capacity, antimalarial
                activity, low unspecific toxicity, specific targeting to
                Plasmodium, optimal in vivo activity and affordable synthesis
                cost. After having shown their efficacy in targeting drugs to
                intraerythrocytic parasites, now polyamidoamines face the
                challenge of spearheading a new generation of nanocarriers
                aiming at the malaria parasite stages in the mosquito vector.

# metadata.dc.relation.isformatof[].value
Versió postprint del document publicat a:
                http://dx.doi.org/10.2217/nnm.15.174

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Polyamidoamine nanoparticles as nanocarriers for the drug
                delivery to malaria parasite stages in the mosquito vector