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Antibiotic prevention of acute exacerbations of COPD

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To the Editor: Wenzel and colleagues (July 26 issue) recommend long-term azithromycin for a 55-year-old man with recurrent exacerbations of chronic obstructive pulmonary disease (COPD), a forced expiratory volume in 1 second (FEV1) of 50% of the predicted value, dyspnea, cough, and sputum production. However, before azithromycin, we think this patient should be treated with other pharmacologic agents to manage his COPD and prevent exacerbations.

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New England Journal of Medicine, 2012, vol. 367, num. 4, p. 340-347

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Articles publicats en revistes (Ciències Clíniques)

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Antibiotic prevention of acute exacerbations of COPD