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Preparation of alpha-labeled aldehydes by base-catalyzed exchange reactions

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A simple, efficient protocol for the preparation of α-labeled aldehydes based on H/D exchange catalyzed by 4-(N,N-dimethylamino)pyridine or Et3N is described. High chemical yields and ratios of isotope incorporation were obtained even when small amounts (1 mmol) of aldehyde were used.

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Journal of Labelled Compounds and Radiopharmaceuticals, 2010, vol. 53, num. 8, p. 556-558

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Articles publicats en revistes (Química Inorgànica i Orgànica)

# metadata.dc.title[].value
Preparation of alpha-labeled aldehydes by base-catalyzed exchange reactions