# name
New transcription regulatory mechanisms of latent HIV LTR

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Despite the effectiveness of antiretroviral medication, the
HIV virus persists in resting memory T cells of infected
patients in a latent state, providing the main impediment
to eradication of the virus. We are interested in identifying
the molecular mechanism responsible for the establishment
and maintenance of HIV latency and its re-activation.
We recently used a cell system reflecting HIV latency
in my lab to determine the high resolution nucleosomal
landscape of the latent HIV LTR and examine its dynamic
changes upon re-activation (Rafati et al., Nov 2011 PLoS
Biology)...

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Retrovirology, 2012, vol. 9, supl. 1, num. O3

# metadata.dc.source[].value
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

# metadata.dc.title[].value
New transcription regulatory mechanisms of latent HIV LTR