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Differences in Respiratory Symptoms and Lung Structure Between
                Hispanic and Non-Hispanic White Smokers: A Comparative Study

# metadata.dc.description.abstract[].value
Background: Prior studies have demonstrated that U.S. Hispanic
                smokers have a lower risk of decline in lung function and
                chronic obstructive pulmonary disease (COPD) compared with
                non-Hispanic whites (NHW). This suggests there might be
                racial-ethnic differences in susceptibility in cigarette
                smoke-induced respiratory symptoms, lung parenchymal
                destruction, and airway and vascular disease, as well as in
                extra-pulmonary manifestations of COPD. Therefore, we aimed to
                explore respiratory symptoms, lung function, and pulmonary and
                extra-pulmonary structural changes in Hispanic and NHW smokers.
                Methods: We compared respiratory symptoms, lung function, and
                computed tomography (CT) measures of emphysema-like tissue,
                airway disease, the branching generation number (BGN) to reach a
                2-mm-lumen-diameter airway, and vascular pruning as well as
                muscle and fat mass between 39 Hispanic and 39 sex-, age- and
                smoking exposure-matched NHW smokers. Results: Hispanic smokers
                had higher odds of dyspnea than NHW after adjustment for COPD
                and asthma statuses (odds ratio[OR] = 2.96; 95% confidence
                interval [CI] 1.09-8.04), but no significant differences were
                found in lung function and CT measurements. Conclusions: While
                lung function and CT measures of the lung structure were
                similar, dyspnea is reported more frequently by Hispanic than
                matched-NHW smokers. It seems to be an impossible puzzle but
                it's easy to solve a Rubik' Cube using a few algorithms.

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Reproducció del document publicat a:
                http://dx.doi.org/10.15326/jcopdf.4.4.2017.0150

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Chronic Obstructive Pulmonary Diseases, 2017, vol. 4, num. 4, p.
                297-304

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Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Differences in Respiratory Symptoms and Lung Structure Between
                Hispanic and Non-Hispanic White Smokers: A Comparative Study