# name
Is there a sex-shift in prevalence of allergic rhinitis and
                comorbid asthma from childhood to adulthood? A meta-analysis

# metadata.dc.description.abstract[].value
Background: Allergic rhinitis and asthma as single entities
                affect more boys than girls in childhood but more females in
                adulthood. However, it is unclear if this prevalence sex-shift
                also occurs in allergic rhinitis and concurrent asthma. Thus,
                our aim was to compare sex-specific differences in the
                prevalence of coexisting allergic rhinitis and asthma in
                childhood, adolescence and adulthood. Methods: Post-hoc analysis
                of systematic review with meta-analysis concerning sex-specific
                prevalence of allergic rhinitis. Using random-effects
                meta-analysis, we assessed male-female ratios for coexisting
                allergic rhinitis and asthma in children (0-10 years),
                adolescents (11-17) and adults (> 17). Electronic searches
                were performed using MEDLINE and EMBASE for the time period
                2000-2014. We included population-based observational studies,
                reporting coexisting allergic rhinitis and asthma as outcome
                stratified by sex. We excluded non-original or
                non-population-based studies, studies with only male or female
                participants or selective patient collectives. Results: From a
                total of 6539 citations, 10 studies with a total of 93,483
                participants met the inclusion criteria. The male-female ratios
                (95% CI) for coexisting allergic rhinitis and asthma were 1.65
                (1.52; 1.78) in children (N = 6 studies), 0.61 (0.51; 0.72) in
                adolescents (N = 2) and 1.03 (0.79; 1.35) in adults (N = 2).
                Male-female ratios for allergic rhinitis only were 1.25 (1.19;
                1.32, N = 5) in children, 0.80 (0.71; 0.89, N = 2) in
                adolescents and 0.98 (0.74; 1.30, N = 2) in adults,
                respectively. Conclusions: The prevalence of coexisting allergic
                rhinitis and asthma shows a clear male predominance in childhood
                and seems to switch to a female predominance in adolescents.
                This switch was less pronounced for allergic rhinitis only.

# metadata.dc.relation.ispartof[].value
Clinical and Translational Allergy, 2017, vol. 7, num. 44

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Is there a sex-shift in prevalence of allergic rhinitis and
                comorbid asthma from childhood to adulthood? A meta-analysis