# name
Actinic Keratosis, a Chronic, Progressive Disease: Understanding Clinical Gaps to Optimise Patient Management

# metadata.dc.description.abstract[].value
Actinic keratosis (AK) is a chronic, progressive disease
of the skin that has undergone long-term sun exposure.
The affected areas contain visible and subclinical nonvisible
sun damage resulting in epidermal keratinocyte
dysplasia, known by many as ‘field cancerisation’ (1),
which is prone to AKs and sun-related skin cancer (2).
Thus, visible AKs are clinical biomarkers for a photo-damaged
field with subclinical damage associated with the
unpredictable risk of progression to invasive squamous
cell carcinoma (iSCC) (3). The aim of this multiexpert
opinion article is to provide a discussion succinctly
highlighting the clinical gaps for optimal management of
AK: the lack of a universal definition and the need for a
standardised grade assessment of AK/field cancerisation
that also takes into account individual risk.

# metadata.dc.rights[].value
cc by-nc (c) Acta Dermato-Venereologica, 2017

# metadata.dc.source[].value
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

# metadata.dc.title[].value
Actinic Keratosis, a Chronic, Progressive Disease: Understanding Clinical Gaps to Optimise Patient Management