# name
Hypoglycemia and Risk Factors for Death in 13 Years of Pediatric
                Admissions in Mozambique

# metadata.dc.description.abstract[].value
Hypoglycemia is a life-threatening complication of several
                diseases in childhood. We describe the prevalence and incidence
                of hypoglycemia among admitted Mozambican children, establishing
                its associated risk factors. We retrospectively reviewed
                clinical data of 13 years collected through an ongoing
                systematic morbidity surveillance in Manhica District Hospital
                in rural Mozambique. Logistic regression was used to identify
                risk factors for hypoglycemia and death. Minimum community-based
                incidence rates (MCBIRs) for hypoglycemia were calculated using
                data from the demographic surveillance system. Of 49,089
                children < 15 years hospitalized in Manhica District
                Hospital, 45,573 (92.8%) had a glycemia assessment on admission.
                A total of 1,478 children (3.2%) presented hypoglycemia (< 3
                mmol/L), of which about two-thirds (972) were with levels <
                2.5 mmol/L. Independent risk factors for hypoglycemia on
                admission and death among hypoglycemic children included
                prostration, unconsciousness, edema, malnutrition, and
                bacteremia. Hypoglycemic children were significantly more likely
                to die (odds ratio [OR] = 7.11; P < 0.001), with an
                associated case fatality rate (CFR) of 19.3% (245/1,267).
                Overall MCBIR of hypoglycemia was 1.57 episodes/1,000 child
                years at risk (CYAR), significantly decreasing throughout the
                study period. Newborns showed the highest incidences (9.47
                episodes/1,000 CYAR, P < 0.001). Hypoglycemia remains a
                hazardous condition for African children. Symptoms and signs
                associated to hypoglycemia should trigger the verification of
                glycemia and the implementation of life-saving corrective
                measures.

# metadata.dc.publisher[].value
American Society of Tropical Medicine and Hygiene

# metadata.dc.relation.isformatof[].value
Versió postprint del document publicat a:
                http://dx.doi.org/10.4269/ajtmh.15-0475

# metadata.dc.relation.ispartof[].value
The American Journal of Tropical Medicine and Hygiene, 2016,
                vol. 94, num. 1, p.

# metadata.dc.rights[].value
(c) American Society of Tropical Medicine and Hygiene, 2016

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Hypoglycemia and Risk Factors for Death in 13 Years of Pediatric
                Admissions in Mozambique