# name
Characterization of Vaginal Escherichia coli Isolated from
                Pregnant Women in Two Different African Sites

# metadata.dc.description.abstract[].value
The relevance of vaginal colonization of pregnant women by
                Escherichia coli is poorly understood, despite these strains
                sharing a similar virulence profile with other extraintestinal
                pathogenic E. coli producing severe obstetric and neonatal
                infections. We characterized the epidemiology, antimicrobial
                susceptibility and virulence profiles of 84 vaginal E. coli
                isolates from pregnant women from Rabat (Morocco) and Manhica
                (Mozambique), two very distinct epidemiological settings. Low
                levels of antimicrobial resistance were observed to all drugs
                tested, except for trimethoprim-sulfamethoxazole in Manhica,
                where this drug is extensively used as prophylaxis for
                opportunistic HIV infections. The most prevalent virulence
                factors were related to iron acquisition systems. Phylogroup A
                was the most common in Rabat, while phylogroups E and
                non-typeable were the most frequent in Manhica. Regardless of
                the apparently "low virulence" of these isolates, the frequency
                of infections is higher and the outcomes more devastating in
                constrained-resources conditions, especially among pregnant
                women and newborns.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.1371/journal.pone.0158695

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Characterization of Vaginal Escherichia coli Isolated from
                Pregnant Women in Two Different African Sites