# name
Role of JNK in neurodegenerative diseases

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Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393

# metadata.dc.description.abstract[].value
The c-Jun N-terminal kinases (JNK) are members of the MAPK family and can be activated by different stimuli such as cellular stress, heat shock and ultra-violet irradiation. JNKs have different physiological functions and they have been linked to apoptosis in different cell types. Therefore, the JNK signalling pathway is an important target to prevent cell death. In the present chapter, the role of JNKs in neurodegenerative diseases will be discussed, as well as the pharmacological compounds that inhibit this signalling pathway as therapeutic intervention to prevent neuronal death.

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Reproducció del capítol 2 del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=131

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Recent Advances in Pharmaceutical Sciences II, 2012, Editor: Diego Muñoz-Torrero, Diego Haro and Joan Vallès, Chapter 2, p. 15-28.

# metadata.dc.source[].value
Llibres / Capítols de llibre (Farmacologia, Toxicologia i Química Terapèutica)

# metadata.dc.title[].value
Role of JNK in neurodegenerative diseases