# name
Radical Cyclization of Trichloroacetamides: Synthesis of Lactams

# metadata.dc.description.abstract[].value
Trichloroacetamides can act as radical precursors to synthesize nitrogen-containing heterocycles in a variety of processes, mainly involving atom transfer radical cyclizations (ATRC), mediated by Cu(I) or Ru(II) catalysts, and the hydride reductive method, employing either Bu3SnH or (Me3Si)3SiH, or recently NaBH3CN. Additionally, amine-mediated single-electron transfer cyclizations, as well as radical processes promoted by Ni, Fe, Mn, Ti, and Ag, have been developed.

# metadata.dc.publisher[].value
Georg Thieme Verlag Stuttgart · New York

# metadata.dc.rights[].value
cc-by-nc-nd (c) Coussanes, G. et al., 2017

# metadata.dc.source[].value
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

# metadata.dc.title[].value
Radical Cyclization of Trichloroacetamides: Synthesis of Lactams