# name
Tying malaria and microRNAs: from the biology to future
                diagnostic perspectives

# metadata.dc.description.abstract[].value
Symptoms caused by bacterial, viral and malarial infections
                usually overlap and aetiologic diagnosis is difficult. Patient
                management in low-resource countries with limited laboratory
                services has been based predominantly on clinical evaluation and
                syndromic approaches. However, such clinical assessment has
                limited accuracy both for identifying the likely aetiological
                cause and for the early recognition of patients who will
                progress to serious or fatal disease. Plasma-detectable
                biomarkers that rapidly and accurately diagnose severe
                infectious diseases could reduce morbidity and decrease the
                unnecessary use of usually scarce therapeutic drugs. The
                discovery of microRNAs (miRNAs) has opened exciting new avenues
                to identify blood biomarkers of organ-specific injury. This
                review assesses current knowledge on the relationship between
                malaria disease and miRNAs, and evaluates how future research
                might lead to the use of these small molecules for identifying
                patients with severe malaria disease and facilitate treatment
                decisions.

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Tying malaria and microRNAs: from the biology to future
                diagnostic perspectives