# name
Ivermectin to reduce malaria transmission I. Pharmacokinetic and
                pharmacodynamic considerations regarding efficacy and safety

# metadata.dc.description.abstract[].value
Ivermectin is an endectocide that has been used broadly in
                single dose community campaigns for the control of
                onchocerciasis and lymphatic filariasis for more than 30 years.
                There is now interest in the potential use of ivermectin
                regimens to reduce malaria transmission, envisaged as
                community-wide campaigns tailored to transmission patterns and
                as complement of the local vector control programme. The
                development of new ivermectin regimens or other novel
                endectocides will require integrated development of the drug in
                the context of traditional entomological tools and endpoints.
                This document examines the main pharmacokinetic and
                pharmacodynamic parameters of the medicine and their potential
                influence on its vector control efficacy and safety at
                population level. This information could be valuable for trial
                design and clinical development into regulatory and policy
                pathways.

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Ivermectin to reduce malaria transmission I. Pharmacokinetic and
                pharmacodynamic considerations regarding efficacy and safety