# name
Continuous determination of blood glucose in children admitted
                with malaria in a rural hospital in Mozambique

# metadata.dc.description.abstract[].value
BACKGROUND: Hypoglycaemia is a frequent complication among
                admitted children, particularly in malaria-endemic areas. This
                study aimed to estimate the occurrence of hypoglycaemia not only
                upon admission but throughout the first 72 h of hospitalization
                in children admitted with malaria. METHODS: A simple pilot study
                to continuously monitor glycaemia in children aged 0-10 years,
                admitted with malaria in a rural hospital was conducted in
                Southern Mozambique by inserting continuous glucose monitors
                (CGMs) in subcutaneous tissue of the abdominal area, producing
                glycaemia readings every 5 min. RESULTS: Glucose was
                continuously monitored during a mean of 48 h, in 74 children.
                Continuous measurements of blood glucose were available for
                72/74 children (97.3%). Sixty-five of them were admitted with
                density-specific malaria diagnosis criteria (17 severe, 48
                uncomplicated). Five children (7.7%) had hypoglycaemia (<54
                mg/dL) on admission as detected by routine capillary
                determination. Analysing the data collected by the CGMs,
                hypoglycaemia episodes (<54 mg/dL) were detected in 10/65
                (15.4%) of the children, of which 7 (10.8%) could be classified
                as severe (</=45 mg/dL). No risk factors were independently
                associated with the presence of at least one episode of
                hypoglycaemia (<54 mg/dL) during hospitalization. Only one
                death occurred among a normoglycaemic child. All episodes of
                hypoglycaemia detected by CGMs were subclinical episodes or not
                perceived by caregivers or clinical staff. CONCLUSIONS:
                Hypoglycaemia beyond admission in children with malaria appears
                to be much more frequent than what had been previously
                described. The clinical relevance of these episodes of
                hypoglycaemia in the medium or long term remains to be
                determined.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.1186/s12936-017-1840-x

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Continuous determination of blood glucose in children admitted
                with malaria in a rural hospital in Mozambique