# name
Short-term exposure to traffic-related air pollution and
                ischemic stroke onset in Barcelona, Spain

# metadata.dc.description.abstract[].value
OBJECTIVE: To assess the relationship between short-term
                exposure to outdoor ambient air pollutants (fine particulate
                matter [PM2.5] and black carbon [BC]), ischemic stroke (IS) and
                its different subtypes, and the potential modifying effect of
                neighborhood greenspace and noise. METHODS: This time-stratified
                case-crossover study was based on IS and transient ischemic
                attacks (TIA) recorded in a hospital-based prospective stroke
                register (BASICMAR 2005-2014) in Barcelona (Catalonia, Spain).
                Daily and hourly pollutant concentrations and meteorological
                data were obtained from monitoring stations in the city.
                Time-lags (from previous 72h to acute stroke onset) were
                analyzed. Greenness and noise were determined from the
                Normalized Difference Vegetation Index (NDVI) and daily average
                noise level at the street nearest to residential address,
                respectively. RESULTS: The 2742 cases with known onset date and
                time, living in the study area, were analyzed. After adjusting
                for temperature, no statistically significant association
                between pollutants exposure and overall stroke risk was found.
                In subtype analysis, an association was detected between BC
                exposure at 24-47h (odds ratio, 1.251; 95% confidence interval
                [CI], 1.001-1.552; P = 0.042) and 48-72h (1.211; 95% CI,
                0.988-1.484; P = 0.065) time-lag prior to stroke onset and
                large-artery atherosclerosis subtype. No clear modifying effect
                of greenness or noise was observed. CONCLUSIONS: Overall, no
                association was found between PM2.5 and BC exposure and acute IS
                risk. By stroke subtype, large-artery atherosclerotic stroke
                could be triggered by daily increases in BC, a diesel
                fuel-related pollutant in the study area.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.1016/j.envres.2017.12.024

# metadata.dc.rights[].value
cc by-nc-nd (c) Vivanco Hidalgo et al., 2018

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Short-term exposure to traffic-related air pollution and
                ischemic stroke onset in Barcelona, Spain