# metadata.dc.description[].value
Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2020, Tutors: Antoni Riera Escalé, Marina Bellido Muñoz

# metadata.dc.description.abstract[].value
The synthesis of chiral compounds has long been a primary goal in the field of catalytic
asymmetric synthesis. The breakthrough of chiral ligands, able to induce excellent
enantioselectivities in many processes, is in line with the measures taken to minimize the
environmental risks in organic synthesis. Among them, P*-stereogenic phosphine ligands are
proficient in inducing chirality to produce optically active compounds in a straightforward and
atom-economic pathway.
On this matter, our group has synthesized building block 1. This P-stereogenic
aminophosphane is prone to providing air-stable chiral ligands by means of a NH/PH tautomeric
equilibrium. The MaxPHOS ligand and the Secondary Iminophosphorane family of ligands (SIPs)
are great examples of its versatility.
In this work, novel ligands for asymmetric catalysis have been developed starting from
privileged intermediate 1. The inspection of the recent literature assisted on the election of the
appropriate modulation while conceiving these ligands.
Afterwards, the scope of application has been considered in the design of the respective
catalysts. Thereby, their rhodium complexes have been prepared, whereas the incorporation of
an inexpensive transition-metal, nickel, has been assessed

# metadata.dc.title.alternative[].value
Lligands P-estereogènics. Estudi bibliogràfic i experimental