# name
Recent advances in understanding lung function development

# metadata.dc.description.abstract[].value
Recent years have witnessed critical contributions to our
                understanding of the determinants and long-term implications of
                lung function development. In this article, we review studies
                that have contributed to advances in understanding lung function
                development and its critical importance for lung health into
                adult life. In particular, we have focused on early life
                determinants that include genetic factors, perinatal events,
                environmental exposures, lifestyle, infancy lower respiratory
                tract infections, and persistent asthma phenotypes. Longitudinal
                studies have conclusively demonstrated that lung function
                deficits that are established by school age may track into adult
                life and increase the risk of adult lung obstructive diseases,
                such as chronic obstructive pulmonary disease. Furthermore,
                these contributions have provided initial evidence in support of
                a direct influence by early life events on an accelerated
                decline of lung function and an increased susceptibility to its
                environmental determinants well into adult life. As such, we
                argue that future health-care programs based on precision
                medicine approaches that integrate deep phenotyping with
                tailored medication and advice to patients should also foster
                optimal lung function growth to be fully effective.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.12688/f1000research.11185.1

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Recent advances in understanding lung function development