# name
Mother's education and offspring asthma risk in 10 European cohort studies

# metadata.dc.description.abstract[].value
Highly prevalent and typically beginning in childhood, asthma is a burdensome disease, yet the risk factors for this condition are not clarified. To enhance understanding, this study assessed the cohort-specific and pooled risk of maternal education on
                asthma in children aged 3-8 across 10 European countries. Data
                on 47,099 children were obtained from prospective birth cohort
                studies across 10 European countries. We calculated
                cohort-specific prevalence difference in asthma outcomes using
                the relative index of inequality (RII) and slope index of
                inequality (SII). Results from all countries were pooled using
                random-effects meta-analysis procedures to obtain mean RII and
                SII scores at the European level. Final models were adjusted for
                child sex, smoking during pregnancy, parity, mother's age and
                ethnicity. The higher the score the greater the magnitude of
                relative (RII, reference 1) and absolute (SII, reference 0)
                inequity. The pooled RII estimate for asthma risk across all
                cohorts was 1.46 (95% CI 1.26, 1.71) and the pooled SII estimate
                was 1.90 (95% CI 0.26, 3.54). Of the countries examined, France,
                the United Kingdom and the Netherlands had the highest
                prevalence's of childhood asthma and the largest inequity in
                asthma risk. Smaller inverse associations were noted for all
                other countries except Italy, which presented contradictory
                scores, but with small effect sizes. Tests for heterogeneity
                yielded significant results for SII scores. Overall, offspring
                of mothers with a low level of education had an increased
                relative and absolute risk of asthma compared to offspring of
                high-educated mothers.

# metadata.dc.relation.ispartof[].value
European Journal of Epidemiology, 2017, vol. , num. , p. Ahead of print

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Mother's education and offspring asthma risk in 10 European cohort studies