# metadata.dc.description[].value
Treballs Finals de Grau de Farmàcia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 2025. Tutora: Fernanda da Silva Andrade

# metadata.dc.description.abstract[].value
Hypertension, commonly known as high blood pressure, is a major global health concern and 
one of the leading risk factors for cardiovascular diseases and chronic kidney disease. It affects 
more than one billion people worldwide, and its prevalence is increasing due to factors such as 
aging populations, sedentary lifestyles, unhealthy diets, and obesity. Hypertension is a chronic 
condition in which the force of blood against the walls of the arteries remains consistently high, 
placing excessive strain on the cardiovascular system. Blood pressure is determined by the 
amount of blood the heart pumps and the resistance of the arteries to blood flow. When this 
balance is disrupted - due to factors such as increased vascular resistance, excessive sodium 
retention, or overactivation of the renin-angiotensin-aldosterone system - blood pressure rises 
and, if left untreated, can lead to severe complications, including damage to vital organs such as 
the heart, kidneys, and brain. Chronic hypertension contributes to the thickening and stiffening 
of arterial walls, reducing their elasticity and increasing the risk of atherosclerosis, a condition 
that can further lead to ischemic events such as heart attacks and strokes. In addition, high blood 
pressure can overwork the heart, leading to left ventricular hypertrophy and, eventually, heart 
failure. In the kidneys, sustained hypertension can impair filtration, leading to chronic kidney 
disease and, in severe cases, kidney failure. Furthermore, hypertension is closely linked to 
cognitive decline and vascular dementia due to its effects on cerebral blood flow. Managing blood 
pressure effectively is essential to reducing the risk of these life-threatening conditions

# metadata.dc.source[].value
Treballs Finals de Grau (TFG) - Farmàcia