# name
Seroprevalence of CMV, HSV-2 and HBV among HIV-Infected Malawian
                Children: A Cross-sectional Survey

# metadata.dc.description.abstract[].value
BACKGROUND: Little is known about viral co-infections in African
                human immunodeficiency virus (HIV)-infected children. We
                examined the prevalence of seromarkers for cytomegalovirus
                (CMV), herpes simplex virus type 2 (HSV-2) and hepatitis B virus
                (HBV) infections among HIV-infected, antiretroviral treatment
                (ART)-naive children in Lilongwe, Malawi. METHODS: Ninety-one
                serum samples were tested for IgG and IgM antibodies to CMV, and
                IgG antibodies to HSV-2 and hepatitis B surface antigen (HBsAg).
                Baseline demographic, clinical and laboratory data were
                abstracted from electronic records. RESULTS: CMV IgG was the
                most common positive result in all age groups (in 73% of
                children <1 year, and 100% in all other groups). Three
                patients were CMV IgM positive (3.3%), suggesting acute
                infection. HSV-2 IgG was positive in four patients (4.4%), and
                HBsAg in two (2.2%). CONCLUSIONS: CMV infection occurred early
                in life, and few children had specific signs of CMV infection at
                the time of ART initiation. Unrecognized HBV infection
                represents opportunities for testing and treatment of HIV/HBV
                co-infected children.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.1093/tropej/fmv105

# metadata.dc.relation.ispartof[].value
Journal of Tropical Pediatrics, 2016, vol. 0, p.1-7

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Seroprevalence of CMV, HSV-2 and HBV among HIV-Infected Malawian
                Children: A Cross-sectional Survey